We’d like to announce an implementation of Protein interaction of CArbohydrates Predictor and CArbohydrate Protein Site IdentiFier 2 (CAPSIF2) app on ROSIE:

PiCAP is a deep learning method that predicts whether a protein binds to carbohydrates/glycans in biological contexts. PiCAP has been used to elucidate the human, mouse, and E. coli proteomes in terms of protein-carbohydrate binding.

CAPSIF2 is a deep learning method that predicts which residues of a provided protein binds to carbohydrates. CAPSIF2 outcompetes current models for residue predictions, such as PeSTo-Carbs.